|Application period ends:||2018-02-11|
|Type of employment:||Fixed-term|
|Description of position:||
We are looking for two summer workers in the discipline of cell biology.
Task 1: Cell culturing and characterization in cells expressing a variety of Ion channels that are believed to be of importance in pain mechanisms. The functionality of these cells is tested by quantifying their Ca release (FLIPR technology) or by Electrophysiological experiments (automated Patch Clamp). Different reference and Orion proprietary compounds are characterized. Imaging techniques are also used.
Task 2: Work with inducible pluripotent stem cells (iPSCs). Development and testing of differentation protocols. Characterization of iPCSs on both RNA and protein levels, testing of functionality. Imaging.
We have planned that the summer work begins in May and lasts about four months. The students can take a summer holiday of three weeks in July. We are open to discuss the opportunity of the chosen students conducting their final thesis with Orion.
|Description of unit:||Discovery Biology & Molecular Profiling unit consist of nearly 20 people working as Principal Scientists, Research / Junior Scientists and Assistants. We belong to the global function of Medicinal Chemistry and we have close collaboration with our chemists who actually make the compounds that we then test in our assays. We work together in teams that vary depending on time, demands and competencies.|
|We offer:||We offer you the opportunity to show your talent in one of the most innovative companies in Finland. We also offer you great colleagues and the opportunity to challenge yourself with interesting tasks. In addition to your own duties, you will get a comprehensive picture of all Orion's activities and numerous different tasks we have. Welcome to build well-being this summer!|
From a successful candidate we are expecting excellent background in cell and molecule biology, both theoretically and from a research lab (for example summer work in a laboratory or equivalent). Practical experience from cell culture is a must. The instruments and techniques can be learned in Orion. We are counting on that the applicants are approaching the end of their education (maximum of 2 years remaining in the master's education).